Efficacy and Mechanism of Action of Rybelsus in Type 2 Diabetes Management
Rybelsus is a brand-name prescription medication that is FDA-approved to treat Type 2 diabetes. The drug will help control your blood sugar when you use it with diet and exercise. Type 2 diabetes is a condition when your blood sugar level becomes too high as the result of problems with a hormone called insulin.
RYBELSUS works differently than the other diabetes medications to lower blood sugar in all three of the following ways:
* Increases insulin when released from the pancreas- It stimulates your pancreas to actually release more insulin when your blood sugar is high.
* Decreases the amount of sugar released from the liver- It prevents your liver from making and then releasing too much sugar.
* Slows down the food- As it leaves your stomach after eating.
How to Properly Use Rybelsus
A good place to start is to read the Medication Guide provided by your pharmacist before you start taking a semaglutide and every time you get a refill. If you have any questions at any time, ask your doctor or pharmacist.
* Take this medication with a small sip of plain water, no more than four ounces, as directed by your doctor, usually once a day. Do not take it with any other beverage. Swallow the tablet whole. Do not split, chew, or even crush the tablet. Wait at least 30 minutes after taking Rybelsus before you eat or drink anything other than water and before taking any other medication orally.
* For the best effect, you should eat 30 to 60 minutes after taking Rybelsus. It is also important to take this medication the same way with every dose.
* The actual dosage is based on your medical condition and your response to the treatment.
* To reduce your risk of any side effects, your doctor might direct you to start this medication at a lower dose and gradually increase it. Follow your doctor’s instructions carefully.
* Use Rybelsus regularly to get the most benefit from it. To help you remember, establish a routine by taking it at the same time each day.
* Do not increase your dose, or take it more often, or longer than prescribed. Your condition will not improve any faster, but your risk of side effects will increase.
Tell your doctor if your condition does not improve or if it gets worse, your blood sugar is either too high or too low.
Efficacy and Success Rates of Using Rybelsus
Many people begin observing modest weight loss within a week or two of starting Rybelsus. In the study referenced showed an average weight loss of 4.4 kg. The study participants saw modest, but steady weight loss until about week 26, after which their weight leveled off.
The OASIS 1 trial, which investigated and researched Rybelsus among 667 adults, concluded that, on an average, individuals taking 50 mg of Rybelsus lost more than 17% of their body weight after 68 weeks. In addition, nearly 40% of the participants achieved weight loss of 20% or more.